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Spatial mapping of collagen content and structure in human intervertebral disk degeneration

Collagen plays a key structural role in both the annulus fibrosus (AF) and nucleus pulposus (NP) of intervertebral disks (IVDs). Changes in collagen content with degeneration suggest a shift from collagen type II to type I within the NP, and the activation of pro‐inflammatory factors is indicative o...

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Publicado en:JOR Spine
Main Authors: Zeldin, Lawrence, Mosley, Grace E., Laudier, Damien, Gallate, Zachary S., Gansau, Jennifer, Hoy, Robert C., Poeran, Jashvant, Iatridis, James C.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley & Sons, Inc. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7770200/
https://ncbi.nlm.nih.gov/pubmed/33392461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jsp2.1129
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