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Vitamin D moderates the interaction between 5-HTTLPR and childhood abuse in depressive disorders

A complex interplay between genetic and environmental factors determines the individual risk of depressive disorders. Vitamin D has been shown to stimulate the expression of the tryptophan hydroxylase 2 (TPH2) gene, which is the rate-limiting enzyme for serotonin production in the brain. Therefore,...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bonk, Sarah, Hertel, Johannes, Zacharias, Helena U., Terock, Jan, Janowitz, Deborah, Homuth, Georg, Nauck, Matthias, Völzke, Henry, Meyer zu Schwabedissen, Henriette, Van der Auwera, Sandra, Grabe, Hans Jörgen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7769965/
https://ncbi.nlm.nih.gov/pubmed/33372187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79388-7
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