Moderation of Adult Depression by a Polymorphism in the FKBP5 Gene and Childhood Physical Abuse in the General Population

Childhood maltreatment and depressive disorders have both been associated with a dysregulation of the hypothalamic–pituitary–adrenal axis. The FKBP5 gene codes for a co-chaperone regulating the glucocorticoid-receptor sensitivity. Previous evidence suggests that subjects carrying the TT genotype of...

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Главные авторы: Appel, Katja, Schwahn, Christian, Mahler, Jessie, Schulz, Andrea, Spitzer, Carsten, Fenske, Kristin, Stender, Jan, Barnow, Sven, John, Ulrich, Teumer, Alexander, Biffar, Reiner, Nauck, Matthias, Völzke, Henry, Freyberger, Harald J, Grabe, Hans J
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2011
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158316/
https://ncbi.nlm.nih.gov/pubmed/21654733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.81
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