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Local cortical overexpression of human wild-type alpha-synuclein leads to increased dendritic spine density in mouse.
Lewy body dementias are characterized by deposition of alpha-synuclein (α-syn) protein aggregates known as Lewy bodies and Lewy neurites in cortical regions, in addition to brainstem. These aggregates are thought to cause the death of dopaminergic neurons in the substantia nigra and other vulnerable...
Shranjeno v:
| izdano v: | Neurosci Lett |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7769708/ https://ncbi.nlm.nih.gov/pubmed/32417387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2020.135051 |
| Oznake: |
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