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Local cortical overexpression of human wild-type alpha-synuclein leads to increased dendritic spine density in mouse.
Lewy body dementias are characterized by deposition of alpha-synuclein (α-syn) protein aggregates known as Lewy bodies and Lewy neurites in cortical regions, in addition to brainstem. These aggregates are thought to cause the death of dopaminergic neurons in the substantia nigra and other vulnerable...
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| 出版年: | Neurosci Lett |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7769708/ https://ncbi.nlm.nih.gov/pubmed/32417387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2020.135051 |
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