Antileishmanial activity of synthetic analogs of the naturally occurring quinolone alkaloid N-methyl-8-methoxyflindersin

Leishmaniasis is a neglected, parasitic tropical disease caused by an intracellular protozoan from the genus Leishmania. Quinoline alkaloids, secondary metabolites found in plants from the Rutaceae family, have antiparasitic activity against Leishmania sp. N-methyl-8-methoxyflindersin (1), isolated...

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Veröffentlicht in:PLoS One
Hauptverfasser: Torres Suarez, Elaine, Granados-Falla, Diana Susana, Robledo, Sara María, Murillo, Javier, Upegui, Yulieth, Delgado, Gabriela
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7769561/
https://ncbi.nlm.nih.gov/pubmed/33370295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0243392
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