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The dirty little secret of urate-lowering therapy: useless to stop chronic kidney disease progression and may increase mortality

Hyperuricaemia is frequent in chronic kidney disease (CKD). Observational studies have shown an association with adverse outcomes and acquired hyperuricaemia (meaning serum urate levels as low as 1.0 mg/dL) in animal models induces kidney injury. This evidence does not justify the widespread use of...

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Detalhes bibliográficos
Publicado no:Clin Kidney J
Main Authors: Gonzalez-Martin, Guillermo, Cano, Jaime, Carriazo, Sol, Kanbay, Mehmet, Perez-Gomez, Maria Vanessa, Fernandez-Prado, Raul, Ortiz, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7769546/
https://ncbi.nlm.nih.gov/pubmed/33391737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ckj/sfaa236
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