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Getting closer to the dirty little secret

The molecular mechanism behind alum adjuvanticity is probably the oldest secret of immunology. In this issue of Immunity, Kuroda et al. (Kuroda, 2011) and Kool et al. (Kool, 2011) identify NLRP3 protein-independent signaling to be crucial for the Th2 cell response induced by aluminum salts.

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Bibliografische gegevens
Hoofdauteurs: Pelka, Karin, Latz, Eicke
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128920/
https://ncbi.nlm.nih.gov/pubmed/21511178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.04.003
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