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How genomics reclassifies diseases: the case of Alport syndrome

In this issue, Matthews et al. provide a comprehensive review of published cohorts with heterozygous pathogenic variants in COL4A3 or COL4A4, documenting the wide spectrum of the disease. Due to the extreme phenotypes that patients with heterozygous pathogenic variants in COL4A3 or COL4A4 may show,...

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Bibliografske podrobnosti
izdano v:Clin Kidney J
Main Authors: Torra, Roser, Furlano, Monica, Ars, Elisabet
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7769510/
https://ncbi.nlm.nih.gov/pubmed/33391736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ckj/sfaa170
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