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Novel homozygous OSGEP gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature

BACKGROUND: Galloway-Mowat syndrome (GAMOS) is a rare autosomal recessive disorder characterized by early-onset nephrotic syndrome and microcephaly with brain anomalies. WDR73 pathogenic variants were described as the first genetic cause of GAMOS and, very recently, four novel causative genes, OSGEP...

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Библиографические подробности
Опубликовано в: :BMC Nephrol
Главные авторы: Domingo-Gallego, Andrea, Furlano, Mónica, Pybus, Marc, Barraca, Daniel, Martínez, Ana Belén, Mora Muñoz, Emiliano, Torra, Roser, Ars, Elisabet
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6458604/
https://ncbi.nlm.nih.gov/pubmed/30975089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12882-019-1317-y
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