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A model for the solution structure of human Fe(II)-bound acireductone dioxygenase and interactions with the regulatory domain of matrix metalloproteinase I (MMP-1)

The metalloenzyme acireductone dioxygenase (ARD) shows metal-dependent physical and enzymatic activities depending upon the metal bound in the active site. The Fe(II)-bound enzyme catalyzes the penultimate step of the methionine salvage pathway (MSP), converting 1,2-dihydroxy-5-(methylthio)pent-1-en...

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Bibliografiske detaljer
Udgivet i:Biochemistry
Main Authors: Liu, Xinyue, Garber, Abigail, Ryan, Julia, Deshpande, Aditi, Ringe, Dagmar, Pochapsky, Thomas C.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7768908/
https://ncbi.nlm.nih.gov/pubmed/33135413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00724
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