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Dual chemistry catalyzed by human acireductone dioxygenase
Acireductone dioxygenase (ARD) from the methionine salvage pathway of Klebsiella oxytoca is the only known naturally occurring metalloenzyme that catalyzes different reactions in vivo based solely on the identity of the divalent transition metal ion (Fe(2+) or Ni(2+)) bound in the active site. The i...
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| Veröffentlicht in: | Protein Eng Des Sel |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5421613/ https://ncbi.nlm.nih.gov/pubmed/28062648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzw078 |
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