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Factors Influencing the Steady-State Plasma Concentration of Imatinib Mesylate in Patients With Gastrointestinal Stromal Tumors and Chronic Myeloid Leukemia

Imatinib mesylate (IM) is the standard treatment for advanced, metastatic gastrointestinal stromal tumors (GISTs) and chronic myeloid leukemia (CML) with a fixed daily standard dosage via the oral route. Interindividual and intraindividual variability in plasma concentrations have been closely linke...

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Bibliografske podrobnosti
izdano v:Front Pharmacol
Main Authors: Chen, Yan, Dong, Xiuhua, Wang, QiuJu, Liu, ZhiXi, Dong, XinWei, Shi, Sanjun, Xiao, HongTao
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7768902/
https://ncbi.nlm.nih.gov/pubmed/33381028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.569843
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