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Factors Influencing the Steady-State Plasma Concentration of Imatinib Mesylate in Patients With Gastrointestinal Stromal Tumors and Chronic Myeloid Leukemia

Imatinib mesylate (IM) is the standard treatment for advanced, metastatic gastrointestinal stromal tumors (GISTs) and chronic myeloid leukemia (CML) with a fixed daily standard dosage via the oral route. Interindividual and intraindividual variability in plasma concentrations have been closely linke...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Chen, Yan, Dong, Xiuhua, Wang, QiuJu, Liu, ZhiXi, Dong, XinWei, Shi, Sanjun, Xiao, HongTao
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7768902/
https://ncbi.nlm.nih.gov/pubmed/33381028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.569843
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