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MicroED structure of lipid-embedded mammalian mitochondrial voltage-dependent anion channel

A structure of the murine voltage-dependent anion channel (VDAC) was determined by microcrystal electron diffraction (MicroED). Microcrystals of an essential mutant of VDAC grew in a viscous bicelle suspension, making it unsuitable for conventional X-ray crystallography. Thin, plate-like crystals we...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Martynowycz, Michael W., Khan, Farha, Hattne, Johan, Abramson, Jeff, Gonen, Tamir
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7768720/
https://ncbi.nlm.nih.gov/pubmed/33293416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2020010117
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