Impaired Hepatic Vitamin A Metabolism in NAFLD Mice Leading to Vitamin A Accumulation in Hepatocytes

BACKGROUND & AIMS: Systemic retinol (vitamin A) homeostasis is controlled by the liver, involving close collaboration between hepatocytes and hepatic stellate cells (HSCs). Genetic variants in retinol metabolism (PNPLA3 and HSD17B13) are associated with non-alcoholic fatty liver disease (NAFLD)...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Mol Gastroenterol Hepatol
Egile Nagusiak: Saeed, Ali, Bartuzi, Paulina, Heegsma, Janette, Dekker, Daphne, Kloosterhuis, Niels, de Bruin, Alain, Jonker, Johan W., van de Sluis, Bart, Faber, Klaas Nico
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2020
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7768561/
https://ncbi.nlm.nih.gov/pubmed/32698042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2020.07.006
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