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Spheroid Fabrication Using Concave Microwells Enhances the Differentiation Efficacy and Function of Insulin-Producing Cells via Cytoskeletal Changes

Pancreatic islet transplantation is the fundamental treatment for insulin-dependent diabetes; however, donor shortage is a major hurdle in its use as a standard treatment. Accordingly, differentiated insulin-producing cells (DIPCs) are being developed as a new islet source. Differentiation efficienc...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Lee, Yu Na, Yi, Hye Jin, Goh, Hanse, Park, Ji Yoon, Ferber, Sarah, Shim, In Kyong, Kim, Song Cheol
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7768489/
https://ncbi.nlm.nih.gov/pubmed/33261076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9122551
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