Application of Concave Microwells to Pancreatic Tumor Spheroids Enabling Anticancer Drug Evaluation in a Clinically Relevant Drug Resistance Model

Intrinsic drug resistance of pancreatic ductal adenocarcinoma (PDAC) warrants studies using models that are more clinically relevant for identifying novel resistance mechanisms as well as for drug development. Tumor spheroids (TS) mimic in vivo tumor conditions associated with multicellular resistan...

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Detalhes bibliográficos
Main Authors: Yeon, Sang-Eun, No, Da Yoon, Lee, Sang-Hoon, Nam, Suk Woo, Oh, Il-Hoan, Lee, Jaehwi, Kuh, Hyo-Jeong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769301/
https://ncbi.nlm.nih.gov/pubmed/24039920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073345
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