Comparison of Colorectal and Endometrial Microsatellite Instability Tumor Analysis and Premm(5) Risk Assessment for Predicting Pathogenic Germline Variants on Multigene Panel Testing

PURPOSE: Tumor testing for microsatellite instability and/or mismatch repair-deficiency (MSI/IHC) and clinical prediction models effectively screen for Lynch syndrome (LS)–associated colorectal cancer (CRC) and endometrial cancer (EC), but they have not been assessed for their ability to identify no...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Mannucci, Alessandro, Furniss, C. Sloane, Ukaegbu, Chinedu, Horiguchi, Miki, Fehlmann, Tara, Uno, Hajime, Yurgelun, Matthew B., Syngal, Sapna
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2020
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ORIGINAL REPORTS
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7768341/
https://ncbi.nlm.nih.gov/pubmed/32997573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.20.01470
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