B7H3-Directed Intraperitoneal Radioimmunotherapy With Radioiodinated Omburtamab for Desmoplastic Small Round Cell Tumor and Other Peritoneal Tumors: Results of a Phase I Study

PURPOSE: Desmoplastic small round cell tumor (DSRCT), a rare sarcoma of adolescents/young adults primarily involving the peritoneum, has a long-term survival of < 20% despite aggressive multimodality treatment. B7H3 is expressed on DSRCT cell surface, providing a target for antibody-based immunot...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Modak, Shakeel, Zanzonico, Pat, Grkovski, Milan, Slotkin, Emily K., Carrasquillo, Jorge A., Lyashchenko, Serge K., Lewis, Jason S., Cheung, Irene Y., Heaton, Todd, LaQuaglia, Michael P., Cheung, Nai-Kong V., Pandit-Taskar, Neeta
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2020
Assuntos:
Original Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7768336/
https://ncbi.nlm.nih.gov/pubmed/33119478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.20.01974
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