TRPM7 Induces Tumorigenesis and Stemness Through Notch Activation in Glioma

We have reported that transient receptor potential melastatin-related 7 (TRPM7) regulates glioma stem cells (GSC) growth and proliferation through Notch, STAT3-ALDH1, and CD133 signaling pathways. In this study, we determined the major contributor(s) to TRPM7 mediated glioma stemness by further deci...

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Dettagli Bibliografici
Pubblicato in:Front Pharmacol
Autori principali: Wan, Jingwei, Guo, Alyssa Aihui, King, Pendelton, Guo, Shanchun, Saafir, Talib, Jiang, Yugang, Liu, Mingli
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7768084/
https://ncbi.nlm.nih.gov/pubmed/33381038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.590723
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