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TRPM7 channels regulate glioma stem cell through STAT3 and Notch signaling pathways
Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumor in adults with median survival time of 14.6 months. A small fraction of cancer stem cells (CSC) initiate and maintain tumors thus driving glioma tumorigenesis and being responsible for resistance to classical chemo-...
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| Опубликовано в: : | Cell Signal |
|---|---|
| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4405379/ https://ncbi.nlm.nih.gov/pubmed/25192910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2014.08.020 |
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