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TRPM7 channels regulate glioma stem cell through STAT3 and Notch signaling pathways

Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumor in adults with median survival time of 14.6 months. A small fraction of cancer stem cells (CSC) initiate and maintain tumors thus driving glioma tumorigenesis and being responsible for resistance to classical chemo-...

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Bibliografiske detaljer
Udgivet i:Cell Signal
Main Authors: Liu, Mingli, Inoue, Koichi, Leng, Tiandong, Guo, Shanchun, Xiong, Zhi-gang
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405379/
https://ncbi.nlm.nih.gov/pubmed/25192910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2014.08.020
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