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TRPM7 channels regulate glioma stem cell through STAT3 and Notch signaling pathways

Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumor in adults with median survival time of 14.6 months. A small fraction of cancer stem cells (CSC) initiate and maintain tumors thus driving glioma tumorigenesis and being responsible for resistance to classical chemo-...

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Detalhes bibliográficos
Publicado no:Cell Signal
Main Authors: Liu, Mingli, Inoue, Koichi, Leng, Tiandong, Guo, Shanchun, Xiong, Zhi-gang
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405379/
https://ncbi.nlm.nih.gov/pubmed/25192910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2014.08.020
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