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ASIC1 promotes differentiation of neuroblastoma by negatively regulating Notch signaling pathway

In neurons, up-regulation of Notch activity either inhibits neurite extension or causes retraction of neurites. Conversely, inhibition of Notch1 facilitates neurite extension. Acid-sensing ion channels (ASICs) are a family of proton-gated cation channels, which play critical roles in synaptic plasti...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Liu, Mingli, Inoue, Koichi, Leng, Tiandong, Zhou, An, Guo, Shanchun, Xiong, Zhi-gang
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352400/
https://ncbi.nlm.nih.gov/pubmed/28030818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14164
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