ASIC1 promotes differentiation of neuroblastoma by negatively regulating Notch signaling pathway

In neurons, up-regulation of Notch activity either inhibits neurite extension or causes retraction of neurites. Conversely, inhibition of Notch1 facilitates neurite extension. Acid-sensing ion channels (ASICs) are a family of proton-gated cation channels, which play critical roles in synaptic plasti...

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Vydáno v:Oncotarget
Hlavní autoři: Liu, Mingli, Inoue, Koichi, Leng, Tiandong, Zhou, An, Guo, Shanchun, Xiong, Zhi-gang
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352400/
https://ncbi.nlm.nih.gov/pubmed/28030818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14164
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