Lack of a Clear Behavioral Phenotype in an Inducible FXTAS Mouse Model Despite the Presence of Neuronal FMRpolyG-Positive Aggregates

Fragile X-associated tremor/ataxia syndrome (FXTAS) is a rare neurodegenerative disorder caused by a 55–200 CGG repeat expansion in the 5′ untranslated region of the Fragile X Mental Retardation 1 (FMR1) gene. FXTAS is characterized by progressive cerebellar ataxia, Parkinsonism, intention tremors a...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Front Mol Biosci
Main Authors: Haify, Saif N., Mankoe, Ruchira S. D., Boumeester, Valerie, van der Toorn, Esmay C., Verhagen, Rob F. M., Willemsen, Rob, Hukema, Renate K., Bosman, Laurens W. J.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Molecular Biosciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7768028/
https://ncbi.nlm.nih.gov/pubmed/33381520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.599101
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker