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Mucin-Like Domain of Mucosal Addressin Cell Adhesion Molecule-1 Facilitates Integrin α4β7-Mediated Cell Adhesion Through Electrostatic Repulsion

The homing of lymphocytes from blood to gut-associated lymphoid tissue is regulated by interaction between integrin α4β7 with mucosal vascular addressin cell adhesion molecule 1 (MAdCAM-1) expressed on the endothelium of high endothelial venules (HEVs). However, the molecular basis of mucin-like dom...

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Pubblicato in:Front Cell Dev Biol
Autori principali: Yuan, MengYa, Yang, YanRong, Li, Yue, Yan, ZhanJun, Lin, ChangDong, Chen, JianFeng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7767916/
https://ncbi.nlm.nih.gov/pubmed/33381505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.603148
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