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Domain 1 of Mucosal Addressin Cell Adhesion Molecule Has an I1-set Fold and a Flexible Integrin-binding Loop
Mucosal addressin cell adhesion molecule (MAdCAM) binds integrin α(4)β(7). Their interaction directs lymphocyte homing to mucosa-associated lymphoid tissues. The interaction between the two immunoglobulin superfamily (IgSF) domains of MAdCAM and integrin α(4)β(7) is unusual in its ability to mediate...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3585063/ https://ncbi.nlm.nih.gov/pubmed/23297416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.413153 |
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