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Domain 1 of Mucosal Addressin Cell Adhesion Molecule Has an I1-set Fold and a Flexible Integrin-binding Loop

Mucosal addressin cell adhesion molecule (MAdCAM) binds integrin α(4)β(7). Their interaction directs lymphocyte homing to mucosa-associated lymphoid tissues. The interaction between the two immunoglobulin superfamily (IgSF) domains of MAdCAM and integrin α(4)β(7) is unusual in its ability to mediate...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Yu, Yamei, Zhu, Jianghai, Huang, Po-Ssu, Wang, Jia-huai, Pullen, Nick, Springer, Timothy A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585063/
https://ncbi.nlm.nih.gov/pubmed/23297416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.413153
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