Domain 1 of Mucosal Addressin Cell Adhesion Molecule Has an I1-set Fold and a Flexible Integrin-binding Loop

Mucosal addressin cell adhesion molecule (MAdCAM) binds integrin α(4)β(7). Their interaction directs lymphocyte homing to mucosa-associated lymphoid tissues. The interaction between the two immunoglobulin superfamily (IgSF) domains of MAdCAM and integrin α(4)β(7) is unusual in its ability to mediate...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Yu, Yamei, Zhu, Jianghai, Huang, Po-Ssu, Wang, Jia-huai, Pullen, Nick, Springer, Timothy A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585063/
https://ncbi.nlm.nih.gov/pubmed/23297416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.413153
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky