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TRPV4 Plays a Role in Matrix Stiffness-Induced Macrophage Polarization

Phenotypic polarization of macrophages is deemed essential in innate immunity and various pathophysiological conditions. We have now determined key aspects of the molecular mechanism by which mechanical cues regulate macrophage polarization. We show that Transient Receptor Potential Vanilloid 4 (TRP...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Dutta, Bidisha, Goswami, Rishov, Rahaman, Shaik O.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7767862/
https://ncbi.nlm.nih.gov/pubmed/33381111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.570195
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