Present Status and Future Trends of Natural-Derived Compounds Targeting T Helper (Th) 17 and Microsomal Prostaglandin E Synthase-1 (mPGES-1) as Alternative Therapies for Autoimmune and Inflammatory-Based Diseases

Several natural-based compounds and products are reported to possess anti-inflammatory and immunomodulatory activity both in vitro and in vivo. The primary target for these activities is the inhibition of eicosanoid-generating enzymes, including phospholipase A2, cyclooxygenases (COXs), and lipoxyge...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Saviano, Anella, Raucci, Federica, Casillo, Gian Marco, Indolfi, Chiara, Pernice, Alessia, Foreste, Carmen, Iqbal, Asif Jilani, Mascolo, Nicola, Maione, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Opinion
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7766998/
https://ncbi.nlm.nih.gov/pubmed/33353211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25246016
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