Epigenetic Modifier SETD8 as a Therapeutic Target for High-Grade Serous Ovarian Cancer

The histone methyltransferase SETD8, which methylates the lysine 20 of histone H4 (H4K20), is reportedly involved in human carcinogenesis along with nonhistone proteins such as p53. However, its expression profiles and functions in the context of high-grade serous ovarian carcinoma (HGSOC) are still...

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Vydáno v:Biomolecules
Hlavní autoři: Wada, Miku, Kukita, Asako, Sone, Kenbun, Hamamoto, Ryuji, Kaneko, Syuzo, Komatsu, Masaaki, Takahashi, Yu, Inoue, Futaba, Kojima, Machiko, Honjoh, Harunori, Taguchi, Ayumi, Kashiyama, Tomoko, Miyamoto, Yuichiro, Tanikawa, Michihiro, Tsuruga, Tetsushi, Mori-Uchino, Mayuyo, Wada-Hiraike, Osamu, Osuga, Yutaka, Fujii, Tomoyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7766894/
https://ncbi.nlm.nih.gov/pubmed/33339442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10121686
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