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Characterization of In Vitro and In Vivo Metabolism of Antazoline Using Liquid Chromatography-Tandem Mass Spectrometry

Antazoline (ANT) was recently shown to be an effective and safe antiarrhythmic drug in the termination of atrial fibrillation. However, the drug is still not listed in clinical guidelines. No data on ANT metabolism in humans is available. We used liquid chromatography coupled with tandem mass spectr...

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Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Giebułtowicz, Joanna, Korytowska, Natalia, Piotrowski, Roman, Kułakowski, Piotr, Latacz, Gniewomir, Szymańska, Ewa, Wiśniowska, Barbara, Polak, Sebastian
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7766522/
https://ncbi.nlm.nih.gov/pubmed/33353167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21249693
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