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Characterization of In Vitro and In Vivo Metabolism of Antazoline Using Liquid Chromatography-Tandem Mass Spectrometry

Antazoline (ANT) was recently shown to be an effective and safe antiarrhythmic drug in the termination of atrial fibrillation. However, the drug is still not listed in clinical guidelines. No data on ANT metabolism in humans is available. We used liquid chromatography coupled with tandem mass spectr...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Giebułtowicz, Joanna, Korytowska, Natalia, Piotrowski, Roman, Kułakowski, Piotr, Latacz, Gniewomir, Szymańska, Ewa, Wiśniowska, Barbara, Polak, Sebastian
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7766522/
https://ncbi.nlm.nih.gov/pubmed/33353167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21249693
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