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Characterization of In Vitro and In Vivo Metabolism of Antazoline Using Liquid Chromatography-Tandem Mass Spectrometry

Antazoline (ANT) was recently shown to be an effective and safe antiarrhythmic drug in the termination of atrial fibrillation. However, the drug is still not listed in clinical guidelines. No data on ANT metabolism in humans is available. We used liquid chromatography coupled with tandem mass spectr...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Giebułtowicz, Joanna, Korytowska, Natalia, Piotrowski, Roman, Kułakowski, Piotr, Latacz, Gniewomir, Szymańska, Ewa, Wiśniowska, Barbara, Polak, Sebastian
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7766522/
https://ncbi.nlm.nih.gov/pubmed/33353167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21249693
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