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In Vivo Bactericidal Efficacy of GWH1 Antimicrobial Peptide Displayed on Protein Nanoparticles, a Potential Alternative to Antibiotics

Oligomerization of antimicrobial peptides into nanosized supramolecular complexes produced in biological systems (inclusion bodies and self-assembling nanoparticles) seems an appealing alternative to conventional antibiotics. In this work, the antimicrobial peptide, GWH1, was N-terminally fused to t...

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Bibliografiske detaljer
Udgivet i:Pharmaceutics
Main Authors: Carratalá, Jose V., Brouillette, Eric, Serna, Naroa, Sánchez-Chardi, Alejandro, Sánchez, Julieta M., Villaverde, Antonio, Arís, Anna, Garcia-Fruitós, Elena, Ferrer-Miralles, Neus, Malouin, François
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7766456/
https://ncbi.nlm.nih.gov/pubmed/33348529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12121217
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