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Design, Synthesis and Comprehensive Investigations of Pyrrolo[3,4-d]pyridazinone-Based 1,3,4-Oxadiazole as New Class of Selective COX-2 Inhibitors

The long-term use of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) in treatment of different chronic inflammatory disorders is strongly restricted by their serious gastrointestinal adverse effects. Therefore, there is still an urgent need to search for new, safe, and efficient anti-inflammatory age...

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Podrobná bibliografie
Vydáno v:Int J Mol Sci
Hlavní autoři: Szczukowski, Łukasz, Krzyżak, Edward, Zborowska, Adrianna, Zając, Patrycja, Potyrak, Katarzyna, Peregrym, Krzysztof, Wiatrak, Benita, Marciniak, Aleksandra, Świątek, Piotr
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7766220/
https://ncbi.nlm.nih.gov/pubmed/33348757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21249623
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