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Design, Synthesis and Comprehensive Investigations of Pyrrolo[3,4-d]pyridazinone-Based 1,3,4-Oxadiazole as New Class of Selective COX-2 Inhibitors

The long-term use of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) in treatment of different chronic inflammatory disorders is strongly restricted by their serious gastrointestinal adverse effects. Therefore, there is still an urgent need to search for new, safe, and efficient anti-inflammatory age...

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Bibliografiska uppgifter
I publikationen:Int J Mol Sci
Huvudupphovsmän: Szczukowski, Łukasz, Krzyżak, Edward, Zborowska, Adrianna, Zając, Patrycja, Potyrak, Katarzyna, Peregrym, Krzysztof, Wiatrak, Benita, Marciniak, Aleksandra, Świątek, Piotr
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7766220/
https://ncbi.nlm.nih.gov/pubmed/33348757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21249623
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