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Single-Cell Transcriptional Profiling of Mouse Islets Following Short-Term Obesogenic Dietary Intervention

Obesity is closely associated with adipose tissue inflammation and insulin resistance. Dysglycemia and type 2 diabetes results when islet β cells fail to maintain appropriate insulin secretion in the face of insulin resistance. To clarify the early transcriptional events leading to β-cell failure in...

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Detalhes bibliográficos
Publicado no:Metabolites
Main Authors: Piñeros, Annie R., Gao, Hongyu, Wu, Wenting, Liu, Yunlong, Tersey, Sarah A., Mirmira, Raghavendra G.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7765825/
https://ncbi.nlm.nih.gov/pubmed/33353164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo10120513
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