Angiopoietin-2 Promotes Inflammatory Activation in Monocytes of Systemic Sclerosis Patients

Angiopoietin-2 (Ang-2), a ligand of the tyrosine kinase receptor Tie2, is essential for vascular development and blood vessel stability and is also involved in monocyte activation. Here, we examined the role of Ang-2 on monocyte activation in patients with systemic sclerosis (SSc). Ang-2 levels were...

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Publicat a:Int J Mol Sci
Autors principals: Carvalheiro, Tiago, Lopes, Ana P., van der Kroef, Maarten, Malvar-Fernandez, Beatriz, Rafael-Vidal, Carlos, Hinrichs, Anneline C., Servaas, Nila H., Bonte-Mineur, Femke, Kok, Marc R., Beretta, Lorenzo, Zimmermann, Maili, Marut, Wioleta, Pego-Reigosa, Jose M., Radstake, Timothy R. D. J., Garcia, Samuel
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7765391/
https://ncbi.nlm.nih.gov/pubmed/33333969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21249544
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