Solid Lipid Curcumin Particles Protect Medium Spiny Neuronal Morphology, and Reduce Learning and Memory Deficits in the YAC128 Mouse Model of Huntington’s Disease

Huntington’s disease (HD) is a genetic neurodegenerative disorder characterized by motor, cognitive, and psychiatric symptoms, accompanied by massive neuronal degeneration in the striatum. In this study, we utilized solid lipid curcumin particles (SLCPs) and solid lipid particles (SLPs) to test thei...

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Publicado en:Int J Mol Sci
Main Authors: Gharaibeh, Abeer, Maiti, Panchanan, Culver, Rebecca, Heileman, Shiela, Srinageshwar, Bhairavi, Story, Darren, Spelde, Kristin, Paladugu, Leela, Munro, Nikolas, Muhn, Nathan, Kolli, Nivya, Rossignol, Julien, Dunbar, Gary L.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7765279/
https://ncbi.nlm.nih.gov/pubmed/33333883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21249542
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