Virus-Like Particle Based Vaccines Elicit Neutralizing Antibodies against the HIV-1 Fusion Peptide

Broadly neutralizing antibodies (bnAbs) isolated from HIV-infected individuals delineate vulnerable sites on the HIV envelope glycoprotein that are potential vaccine targets. A linear epitope within the N-terminal region of the HIV-1 fusion peptide (FP8) is the primary target of VRC34.01, a bnAb tha...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Vaccines (Basel)
Prif Awduron: Mogus, Alemu Tekewe, Liu, Lihong, Jia, Manxue, Ajayi, Diane T., Xu, Kai, Kong, Rui, Huang, Jing, Yu, Jian, Kwong, Peter D., Mascola, John R., Ho, David D., Tsuji, Moriya, Chackerian, Bryce
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7765226/
https://ncbi.nlm.nih.gov/pubmed/33333740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8040765
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