Virus-Like Particle Based Vaccines Elicit Neutralizing Antibodies against the HIV-1 Fusion Peptide

Broadly neutralizing antibodies (bnAbs) isolated from HIV-infected individuals delineate vulnerable sites on the HIV envelope glycoprotein that are potential vaccine targets. A linear epitope within the N-terminal region of the HIV-1 fusion peptide (FP8) is the primary target of VRC34.01, a bnAb tha...

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Détails bibliographiques
Publié dans:Vaccines (Basel)
Auteurs principaux: Mogus, Alemu Tekewe, Liu, Lihong, Jia, Manxue, Ajayi, Diane T., Xu, Kai, Kong, Rui, Huang, Jing, Yu, Jian, Kwong, Peter D., Mascola, John R., Ho, David D., Tsuji, Moriya, Chackerian, Bryce
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7765226/
https://ncbi.nlm.nih.gov/pubmed/33333740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8040765
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