Virus-Like Particle Based Vaccines Elicit Neutralizing Antibodies against the HIV-1 Fusion Peptide

Broadly neutralizing antibodies (bnAbs) isolated from HIV-infected individuals delineate vulnerable sites on the HIV envelope glycoprotein that are potential vaccine targets. A linear epitope within the N-terminal region of the HIV-1 fusion peptide (FP8) is the primary target of VRC34.01, a bnAb tha...

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Detalhes bibliográficos
Publicado no:Vaccines (Basel)
Main Authors: Mogus, Alemu Tekewe, Liu, Lihong, Jia, Manxue, Ajayi, Diane T., Xu, Kai, Kong, Rui, Huang, Jing, Yu, Jian, Kwong, Peter D., Mascola, John R., Ho, David D., Tsuji, Moriya, Chackerian, Bryce
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7765226/
https://ncbi.nlm.nih.gov/pubmed/33333740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8040765
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