Elevated Production of Mitochondrial Reactive Oxygen Species via Hyperthermia Enhanced Cytotoxic Effect of Doxorubicin in Human Breast Cancer Cell Lines MDA-MB-453 and MCF-7

Hyperthermia (HT) treatment is a noninvasive cancer therapy, often used with radiation therapy and chemotherapy. Compared with 37 °C, 42 °C is mild heat stress for cells and produces reactive oxygen species (ROS) from mitochondria. To involve subsequent intracellular accumulation of DOX, we have pre...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Terasaki, Azusa, Kurokawa, Hiromi, Ito, Hiromu, Komatsu, Yoshiki, Matano, Daisuke, Terasaki, Masahiko, Bando, Hiroko, Hara, Hisato, Matsui, Hirofumi
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7765207/
https://ncbi.nlm.nih.gov/pubmed/33333736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21249522
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