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Hyperthermia enhances photodynamic therapy by regulation of HCP1 and ABCG2 expressions via high level ROS generation

Photodynamic therapy (PDT) is a cancer treatment that make use of the cancer-specific accumulation of porphyrins. We have reported that mitochondrial reactive oxygen species (mitROS) upregulate uptake transporter of porphyrins, heme carrier protein-1 (HCP-1). The accumulation of cancer-specific porp...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kurokawa, Hiromi, Ito, Hiromu, Terasaki, Masahiko, Matsui, Hirofumi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6367329/
https://ncbi.nlm.nih.gov/pubmed/30733583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-38460-z
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