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Selective targeting of different populations of myeloid-derived suppressor cells by histone deacetylase inhibitors
Myeloid-derived suppressor cells (MDSCs) are widely implicated in negative regulation of immune responses in cancer. Inhibition of class I histone deacetylases (HDAC) with entinostat has anti-MDSC activity. However, as single agent, it did not delay tumor growth in EL4 and LLC tumor models. Here, we...
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| Publicado no: | Cancer Immunol Immunother |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7765083/ https://ncbi.nlm.nih.gov/pubmed/32435850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-020-02588-7 |
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