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Inhibition of p300 by Garcinol Protects against Cisplatin-Induced Acute Kidney Injury through Suppression of Oxidative Stress, Inflammation, and Tubular Cell Death in Mice

Emerging evidence suggests that epigenetic mechanisms such as histone modification are crucially involved in the pathophysiology of acute kidney injury (AKI). The histone acetyltransferase p300 regulates several biological processes through the acetylation of histones or transcription factors. Howev...

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Bibliografiske detaljer
Udgivet i:Antioxidants (Basel)
Main Authors: Kim, Jung-Yeon, Jo, Jungmin, Leem, Jaechan, Park, Kwan-Kyu
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7765028/
https://ncbi.nlm.nih.gov/pubmed/33327548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9121271
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