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Inhibition of p300 by Garcinol Protects against Cisplatin-Induced Acute Kidney Injury through Suppression of Oxidative Stress, Inflammation, and Tubular Cell Death in Mice

Emerging evidence suggests that epigenetic mechanisms such as histone modification are crucially involved in the pathophysiology of acute kidney injury (AKI). The histone acetyltransferase p300 regulates several biological processes through the acetylation of histones or transcription factors. Howev...

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Publicado en:Antioxidants (Basel)
Main Authors: Kim, Jung-Yeon, Jo, Jungmin, Leem, Jaechan, Park, Kwan-Kyu
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7765028/
https://ncbi.nlm.nih.gov/pubmed/33327548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9121271
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