TXNIP Regulates Natural Killer Cell-Mediated Innate Immunity by Inhibiting IFN-γ Production during Bacterial Infection

The function of natural killer (NK) cell-derived interferon-γ (IFN-γ) expands to remove pathogens by increasing the ability of innate immune cells. Here, we identified the critical role of thioredoxin-interacting protein (TXNIP) in the production of IFN-γ in NK cells during bacterial infection. TXNI...

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Udgivet i:Int J Mol Sci
Main Authors: Kim, Dong Oh, Byun, Jae-Eun, Kim, Won Sam, Kim, Mi Jeong, Choi, Jung Ha, Kim, Hanna, Choi, Eunji, Kim, Tae-Don, Yoon, Suk Ran, Noh, Ji-Yoon, Park, Young-Jun, Lee, Jungwoon, Cho, Hee Jun, Lee, Hee Gu, Min, Sang-Hyun, Choi, Inpyo, Jung, Haiyoung
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7765025/
https://ncbi.nlm.nih.gov/pubmed/33327533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21249499
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