TXNIP regulates AKT‐mediated cellular senescence by direct interaction under glucose‐mediated metabolic stress

Aging is associated with an inevitable and universal loss of cell homeostasis and restricts an organism's lifespan by an increased susceptibility to diseases and tissue degeneration. The glucose uptake associated with producing energy for cell survival is one of the major causes of ROS producti...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Aging Cell
Prif Awduron: Huy, Hangsak, Song, Hae Young, Kim, Mi Jeong, Kim, Won Sam, Kim, Dong Oh, Byun, Jae‐Eun, Lee, Jungwoon, Park, Young‐Jun, Kim, Tae‐Don, Yoon, Suk Ran, Choi, Eun‐Ji, Lee, Chul‐Ho, Noh, Ji‐Yoon, Jung, Haiyoung, Choi, Inpyo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2018
Pynciau:
Original Papers
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260918/
https://ncbi.nlm.nih.gov/pubmed/30168649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12836
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