TXNIP regulates AKT‐mediated cellular senescence by direct interaction under glucose‐mediated metabolic stress

Aging is associated with an inevitable and universal loss of cell homeostasis and restricts an organism's lifespan by an increased susceptibility to diseases and tissue degeneration. The glucose uptake associated with producing energy for cell survival is one of the major causes of ROS producti...

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Detalhes bibliográficos
Publicado no:Aging Cell
Principais autores: Huy, Hangsak, Song, Hae Young, Kim, Mi Jeong, Kim, Won Sam, Kim, Dong Oh, Byun, Jae‐Eun, Lee, Jungwoon, Park, Young‐Jun, Kim, Tae‐Don, Yoon, Suk Ran, Choi, Eun‐Ji, Lee, Chul‐Ho, Noh, Ji‐Yoon, Jung, Haiyoung, Choi, Inpyo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260918/
https://ncbi.nlm.nih.gov/pubmed/30168649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12836
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