TXNIP regulates AKT‐mediated cellular senescence by direct interaction under glucose‐mediated metabolic stress

Aging is associated with an inevitable and universal loss of cell homeostasis and restricts an organism's lifespan by an increased susceptibility to diseases and tissue degeneration. The glucose uptake associated with producing energy for cell survival is one of the major causes of ROS producti...

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Pubblicato in:Aging Cell
Autori principali: Huy, Hangsak, Song, Hae Young, Kim, Mi Jeong, Kim, Won Sam, Kim, Dong Oh, Byun, Jae‐Eun, Lee, Jungwoon, Park, Young‐Jun, Kim, Tae‐Don, Yoon, Suk Ran, Choi, Eun‐Ji, Lee, Chul‐Ho, Noh, Ji‐Yoon, Jung, Haiyoung, Choi, Inpyo
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
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Original Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260918/
https://ncbi.nlm.nih.gov/pubmed/30168649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12836
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