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P27 Protects Neurons from Ischemic Damage by Suppressing Oxidative Stress and Increasing Autophagy in the Hippocampus

p27(Kip1) (p27), a well-known cell regulator, is involved in the regulation of cell death and survival. In the present study, we observed the effects of p27 against oxidative stress induced by H(2)O(2) in HT22 cells and transient ischemia in gerbils. Tat (trans-acting activator of transcription) pep...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kim, Woosuk, Kwon, Hyun Jung, Jung, Hyo Young, Hahn, Kyu Ri, Yoon, Yeo Sung, Hwang, In Koo, Choi, Soo Young, Kim, Dae Won
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7764997/
https://ncbi.nlm.nih.gov/pubmed/33327462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21249496
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