Heat shock protein 70 increases cell proliferation, neuroblast differentiation, and the phosphorylation of CREB in the hippocampus

Abstract In the present study, we investigated the effects of heat shock protein 70 (HSP70) on novel object recognition, cell proliferation, and neuroblast differentiation in the hippocampus. To facilitate penetration into the blood–brain barrier and neuronal plasma membrane, we created a Tat-HSP70...

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Main Authors: Hyun Jung Kwon, Woosuk Kim, Hyo Young Jung, Min Soo Kang, Jong Whi Kim, Kyu Ri Hahn, Dae Young Yoo, Yeo Sung Yoon, In Koo Hwang, Dae Won Kim
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2019-11-01
Series:Laboratory Animal Research
Assuntos:
cAMP response element-binding protein
Cell proliferation
Heat shock protein 70
Hippocampus
Neuroblast differentiation
Novel object recognition
Acceso en liña:http://link.springer.com/article/10.1186/s42826-019-0020-2
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