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Picomolar SARS-CoV-2 Neutralization Using Multi-Arm PEG Nanobody Constructs

Multivalent antibody constructs have a broad range of clinical and biotechnological applications. Nanobodies are especially useful as components for multivalent constructs as they allow increased valency while maintaining a small molecule size. We here describe a novel, rapid method for the generati...

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Bibliografski detalji
Izdano u:Biomolecules
Glavni autori: Moliner-Morro, Ainhoa, J. Sheward, Daniel, Karl, Vivien, Perez Vidakovics, Laura, Murrell, Ben, McInerney, Gerald M., Hanke, Leo
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7764822/
https://ncbi.nlm.nih.gov/pubmed/33322557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10121661
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