Development of a Pharmacogenetic Lab-on-Chip Assay Based on the In-Check Technology to Screen for Genetic Variations Associated to Adverse Drug Reactions to Common Chemotherapeutic Agents

Background: Antineoplastic agents represent the most common class of drugs causing Adverse Drug Reactions (ADRs). Mutant alleles of genes coding for drug-metabolizing enzymes are the best studied individual risk factors for these ADRs. Although the correlation between genetic polymorphisms and ADRs...

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Publicado en:Biosensors (Basel)
Main Authors: Iemmolo, Rosario, La Cognata, Valentina, Morello, Giovanna, Guarnaccia, Maria, Arbitrio, Mariamena, Alessi, Enrico, Cavallaro, Sebastiano
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7764726/
https://ncbi.nlm.nih.gov/pubmed/33317085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/bios10120202
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