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Genotyping of KRAS Mutational Status by the In-Check Lab-on-Chip Platform

The KRAS oncogene is involved in the pathogenesis of several types of cancer, particularly colorectal cancer (CRC). The most frequent mutations in this gene are associated with poor survival, increased tumor aggressiveness and resistance to therapy with anti-epidermal growth factor receptor (EGFR) a...

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Détails bibliographiques
Publié dans:Sensors (Basel)
Auteurs principaux: Guarnaccia, Maria, Iemmolo, Rosario, San Biagio, Floriana, Alessi, Enrico, Cavallaro, Sebastiano
Format: Artigo
Langue:Inglês
Publié: MDPI 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5795341/
https://ncbi.nlm.nih.gov/pubmed/29304017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/s18010131
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