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A GSH-Responsive Nanoprodrug System Based on Self-Assembly of Lactose Modified Camptothecin for Targeted Drug Delivery and Combination Chemotherapy

BACKGROUND: Conventional chemotherapy using small molecular antitumor drugs suffers from several limitations, for instance poor water solubility, high toxicity, and lack of specificity. However, prodrugs constructed by covalent modification of anticancer drugs can overcome these limitations, which a...

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Vydáno v:Int J Nanomedicine
Hlavní autoři: Hou, Chenxi, Ma, Ning, Shen, Ziyan, Chi, Guanyu, Chao, Shuang, Pei, Yuxin, Chen, Lan, Lu, Yuchao, Pei, Zhichao
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7764549/
https://ncbi.nlm.nih.gov/pubmed/33376329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S276470
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