Impact of the Tumor Microenvironment on Tumor Heterogeneity and Consequences for Cancer Cell Plasticity and Stemness

SIMPLE SUMMARY: The cancer cells in solid tumors are embedded in a complex connective tissue matrix composed of various other cell types, i.e., mesenchymal stroma/stem-like cells (MSCs) and tumor-associated macrophages (TAMs). This tumor microenvironment (TME) is considered the major cause of tumor...

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Udgivet i:Cancers (Basel)
Main Authors: Hass, Ralf, von der Ohe, Juliane, Ungefroren, Hendrik
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7764513/
https://ncbi.nlm.nih.gov/pubmed/33322354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12123716
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